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Detection of circulating tumor cells in advanced renal cell carcinoma patients using microfilter-based capture

Mittal, K. and Williams, A. and Rawal, S. and Ao, Z. and Lu, B. and Torres-Munoz, J. and Borden, E. and O’Malley, M. and Woodney, L. and Zheng, S. and Datar, R. and Tai, Y.-C. and Cote, R. and Rini, B. (2012) Detection of circulating tumor cells in advanced renal cell carcinoma patients using microfilter-based capture. BJU International, 110 (S1). p. 9. ISSN 1464-4096 . http://resolver.caltech.edu/CaltechAUTHORS:20121026-085641712

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Abstract

Circulating tumor cells (CTCs) have generated considerable interest as predictive and prognostic biomarkers in solid tumors. While the current FDA approved technology utilizes epithelial cell adhesion molecule (EpCAM) expression for CTC detection, renal cell carcinoma (RCC) cells do not consistently express EpCAM. Based on size differences between larger epithelial tumor cells and smaller nontumor blood cells, CTCs can also be detected using a parylene-based microfilter device.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1111/j.1464-410X.2012.011429.xDOIUNSPECIFIED
http://onlinelibrary.wiley.com/doi/10.1111/j.1464-410X.2012.011429.x/abstractPublisherUNSPECIFIED
ORCID:
AuthorORCID
Tai, Y.-C.0000-0001-8529-106X
Additional Information:© 2012 The Authors. BJU International © 2012 BJU International. Article first published online: 10 Oct. 2012.
Record Number:CaltechAUTHORS:20121026-085641712
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:20121026-085641712
Official Citation:Artibani, W. (2012), Landmarks in prostate cancer diagnosis: the biomarkers. BJU International, 110: 8–13. doi: 10.1111/j.1464-410X.2012.011429.x
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:35115
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:26 Oct 2012 23:45
Last Modified:17 May 2017 20:59

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