Imamoglu, Fatma and Kahnt, Thorsten and Koch, Christof and Haynes, John-Dylan (2012) Changes in functional connectivity support conscious object recognition. NeuroImage, 63 (4). pp. 1909-1917. ISSN 1053-8119. doi:10.1016/j.neuroimage.2012.07.056. https://resolver.caltech.edu/CaltechAUTHORS:20121203-103832550
![]()
|
PDF (Supplementary Materials)
- Supplemental Material
See Usage Policy. 1MB |
Use this Persistent URL to link to this item: https://resolver.caltech.edu/CaltechAUTHORS:20121203-103832550
Abstract
What are the brain mechanisms that mediate conscious object recognition? To investigate this question, it is essential to distinguish between brain processes that cause conscious recognition of a stimulus from other correlates of its sensory processing. Previous fMRI studies have identified large-scale brain activity ranging from striate to high-level sensory and prefrontal regions associated with conscious visual perception or recognition. However, the possible role of changes in connectivity during conscious perception between these regions has only rarely been studied. Here, we used fMRI and connectivity analyses, together with 120 custom-generated, two-tone, Mooney images to directly assess whether conscious recognition of an object is accompanied by a dynamical change in the functional coupling between extrastriate cortex and prefrontal areas. We compared recognizing an object versus not recognizing it in 19 naïve subjects using two different response modalities. We find that connectivity between the extrastriate cortex and the dorsolateral prefrontal cortex (DLPFC) increases when objects are consciously recognized. This interaction was independent of the response modality used to report conscious recognition. Furthermore, computing the difference in Granger causality between recognized and not recognized conditions reveals stronger feedforward connectivity than feedback connectivity when subjects recognized the objects. We suggest that frontal and visual brain regions are part of a functional network that supports conscious object recognition by changes in functional connectivity.
Item Type: | Article | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
Related URLs: |
| |||||||||
ORCID: |
| |||||||||
Additional Information: | © 2012 Elsevier Inc. Accepted 25 July 2012; available online 2 August 2012. We thank Jakob Heinzle for valuable comments. This work was supported by the German Research Foundation (Deutsche Forschungsgemeinschaft, DFG) Grants HA 5336/1-1, KFO247, and the Mathers Charitable Foundation. | |||||||||
Funders: |
| |||||||||
Subject Keywords: | Conscious object recognition; Functional connectivity; Granger causality | |||||||||
Issue or Number: | 4 | |||||||||
DOI: | 10.1016/j.neuroimage.2012.07.056 | |||||||||
Record Number: | CaltechAUTHORS:20121203-103832550 | |||||||||
Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20121203-103832550 | |||||||||
Official Citation: | Fatma Imamoglu, Thorsten Kahnt, Christof Koch, John-Dylan Haynes, Changes in functional connectivity support conscious object recognition, NeuroImage, Volume 63, Issue 4, December 2012, Pages 1909-1917, ISSN 1053-8119, 10.1016/j.neuroimage.2012.07.056. | |||||||||
Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | |||||||||
ID Code: | 35764 | |||||||||
Collection: | CaltechAUTHORS | |||||||||
Deposited By: | Jason Perez | |||||||||
Deposited On: | 03 Dec 2012 18:55 | |||||||||
Last Modified: | 09 Nov 2021 23:17 |
Repository Staff Only: item control page