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Dorsomedial Prefrontal Cortex Mediates Rapid Evaluations Predicting the Outcome of Romantic Interactions

Cooper, Jeffrey C. and Dunne, Simon and Furey, Teresa and O'Doherty, John P. (2012) Dorsomedial Prefrontal Cortex Mediates Rapid Evaluations Predicting the Outcome of Romantic Interactions. Journal of Neuroscience, 32 (45). pp. 15647-15656. ISSN 0270-6474. PMCID PMC3513285. doi:10.1523/JNEUROSCI.2558-12.2012. https://resolver.caltech.edu/CaltechAUTHORS:20121207-095218292

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Abstract

Humans frequently make real-world decisions based on rapid evaluations of minimal information; for example, should we talk to an attractive stranger at a party? Little is known, however, about how the brain makes rapid evaluations with real and immediate social consequences. To address this question, we scanned participants with functional magnetic resonance imaging (fMRI) while they viewed photos of individuals that they subsequently met at real-life “speed-dating” events. Neural activity in two areas of dorsomedial prefrontal cortex (DMPFC), paracingulate cortex, and rostromedial prefrontal cortex (RMPFC) was predictive of whether each individual would be ultimately pursued for a romantic relationship or rejected. Activity in these areas was attributable to two distinct components of romantic evaluation: either consensus judgments about physical beauty (paracingulate cortex) or individualized preferences based on a partner's perceived personality (RMPFC). These data identify novel computational roles for these regions of the DMPFC in even very rapid social evaluations. Even a first glance, then, can accurately predict romantic desire, but that glance involves a mix of physical and psychological judgments that depend on specific regions of DMPFC.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1523/JNEUROSCI.2558-12.2012DOIArticle
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3513285/PubMed CentralArticle
ORCID:
AuthorORCID
Dunne, Simon0000-0003-4875-7953
O'Doherty, John P.0000-0003-0016-3531
Additional Information:© 2012 the authors. Received May 24, 2012; revised July 28, 2012; accepted Aug. 25, 2012. This work was supported by an Irish Research Council on Science, Engineering, and Technology fellowship to J.C.C., a Wellcome Trust project grant, and a Gordon and Betty Moore Foundation grant to J.P.O. We gratefully acknowledge technical assistance from Sojo Joseph and research assistance from Jamie Gallagher, Betsy Carroll, and the Science Gallery. Author contributions: J.C.C. and J.P.O. designed research; J.C.C., S.D., and T.F. performed research; J.C.C., S.D., T.F., and J.P.O. analyzed data; J.C.C. and J.P.O. wrote the paper.
Funders:
Funding AgencyGrant Number
Irish Research Council on Science, Engineering, and TechnologyUNSPECIFIED
Wellcome TrustUNSPECIFIED
Gordon and Betty Moore FoundationUNSPECIFIED
Issue or Number:45
PubMed Central ID:PMC3513285
DOI:10.1523/JNEUROSCI.2558-12.2012
Record Number:CaltechAUTHORS:20121207-095218292
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20121207-095218292
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:35870
Collection:CaltechAUTHORS
Deposited By: Jason Perez
Deposited On:10 Dec 2012 16:45
Last Modified:09 Nov 2021 23:18

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