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The social brain in psychiatric and neurological disorders

Kennedy, Daniel P. and Adolphs, Ralph (2012) The social brain in psychiatric and neurological disorders. Trends in Cognitive Sciences, 16 (11). pp. 559-572. ISSN 1364-6613. PMCID PMC3606817.

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Psychiatric and neurological disorders have historically provided key insights into the structure-function relationships that subserve human social cognition and behavior, informing the concept of the 'social brain'. In this review, we take stock of the current status of this concept, retaining a focus on disorders that impact social behavior. We discuss how the social brain, social cognition, and social behavior are interdependent, and emphasize the important role of development and compensation. We suggest that the social brain, and its dysfunction and recovery, must be understood not in terms of specific structures, but rather in terms of their interaction in large-scale networks.

Item Type:Article
Related URLs:
URLURL TypeDescription DOIArticle CentralArticle
Kennedy, Daniel P.0000-0002-5915-0893
Adolphs, Ralph0000-0002-8053-9692
Additional Information:© 2012 Elsevier Ltd. We thank Jed Elison, John Constantino, Bob Spunt, and three anonymous reviewers for comments. Supported by grants from the NIMH to R.A. (R01MH080721; P50MH094258) and D.P.K. (K99 MH094409).
Funding AgencyGrant Number
NIHK99 MH094409
National Institute of Mental Health (NIMH)UNSPECIFIED
Subject Keywords:social brain; social cognition; brain networks; psychiatry; neurology; amygdala
Issue or Number:11
PubMed Central ID:PMC3606817
Record Number:CaltechAUTHORS:20130102-144935493
Persistent URL:
Official Citation:Daniel P. Kennedy, Ralph Adolphs, The social brain in psychiatric and neurological disorders, Trends in Cognitive Sciences, Volume 16, Issue 11, November 2012, Pages 559-572, ISSN 1364-6613, 10.1016/j.tics.2012.09.006.
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:36126
Deposited By: Tony Diaz
Deposited On:10 Jan 2013 19:40
Last Modified:03 Oct 2019 04:35

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