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Norepinephrine in the brain is associated with aversion to financial loss

Takahashi, H. and Fujie, S. and Camerer, C. and Arakawa, R. and Takano, H. and Kodaka, F. and Matsui, H. and Ideno, T. and Okubo, S. and Takemura, K. and Yamada, M. and Eguchi, Y. and Murai, T. and Okubo, Y. and Kato, M. and Ito, H. and Suhara, T. (2013) Norepinephrine in the brain is associated with aversion to financial loss. Molecular Psychiatry, 18 (1). pp. 3-4. ISSN 1359-4184. http://resolver.caltech.edu/CaltechAUTHORS:20130125-103125495

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Abstract

Understanding the molecular mechanism of extreme or impaired decision-making observed in neuropsychiatric disorders, such as pathological gambling and attention-deficit hyperactivity disorder (ADHD), could contribute to better assessment and the development of novel pharmacological therapies for those disorders. Typically, most people show a disproportionate distaste for possible losses compared with equal-sized gains. This human in vivo molecular imaging study has demonstrated that individuals with lower thalamic norepinephrine transporters (NET) showed more exaggerated aversion to financial loss.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1038/mp.2012.7DOIArticle
http://www.nature.com/mp/journal/v18/n1/full/mp20127a.htmlPublisherArticle
ORCID:
AuthorORCID
Camerer, C.0000-0003-4049-1871
Additional Information:© 2013 Nature Publishing Group, a division of Macmillan Publishers Limited. Published online 21 February 2012. A part of this study is the result of ‘Integrated research on neuropsychiatric disorders’ carried out under the Strategic Research Program for Brain Sciences by the Ministry of Education, Culture, Sports, Science and Technology of Japan (MEXT). This work was supported by Grants-in-aid for Scientific Research (23120009, 23680045), Takeda Science Foundation and Casio Science Foundation.
Funders:
Funding AgencyGrant Number
Ministry of Education, Culture, Sports, Science and Technology (MEXT)UNSPECIFIED
Japan Society for the Promotion of Science (JSPS)23120009
Japan Society for the Promotion of Science (JSPS)23680045
Takeda Science FoundationUNSPECIFIED
Casio Science FoundationUNSPECIFIED
Record Number:CaltechAUTHORS:20130125-103125495
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:20130125-103125495
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:36591
Collection:CaltechAUTHORS
Deposited By: Jason Perez
Deposited On:25 Jan 2013 21:00
Last Modified:09 Jan 2017 03:31

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