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Beyond Watson and Crick: Programming DNA Self-assembly for Nanofabrication

Rothemund, Paul W. K. (2012) Beyond Watson and Crick: Programming DNA Self-assembly for Nanofabrication. In: IEEE-NEMS 2012: 2012 7th IEEE International Conference on Nano/Micro Engineered and Molecular Systems. IEEE , Piscataway, NJ, pp. 1-2. ISBN 978-1-4673-1122-9.

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The specificity of Watson-Crick base-pairing allows great control over the design and synthesis of artificial DNA nanostructures. Periodic one-dimensional (1D) tubes, 2D lattices, and 3D crystals are easily created from “DNA tiles” with spacings of 10-20 nanometers. “DNA origami” allows the folding of long DNA strands into arbitrary shapes and patterns up to about 100 nanometers in size with five nanometer features. This suggests that DNA self-assembly might be used for sublithographic fabrication of devices or even circuits. There are, however, a number of challenges. For example, compared to the inorganic materials used as semiconductors, DNA has poor electronic properties and must be augmented by other materials. Such challenges must be solved before DNA self-assembly can be used in a complete process for nanofabrication. We will present partial solutions to a few of them.

Item Type:Book Section
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Rothemund, Paul W. K.0000-0002-1653-3202
Additional Information:© 2012 IEEE.
Subject Keywords:DNA; self-assembly; nanofabrication
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INSPEC Accession Number12725704
Record Number:CaltechAUTHORS:20130409-135916746
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Official Citation:Rothemund, P.W.K., "Beyond Watson and Crick: Programming DNA self-assembly for nanofabrication," Nano/Micro Engineered and Molecular Systems (NEMS), 2012 7th IEEE International Conference on , vol., no., pp.1,2, 5-8 March 2012 doi: 10.1109/NEMS.2012.6196703
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:37832
Deposited By: Ruth Sustaita
Deposited On:09 Apr 2013 21:38
Last Modified:09 Nov 2021 23:31

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