A Caltech Library Service

Genetic approaches to study of biofilms

O'Toole, George A. and Pratt, Leslie A. and Watnick, Paula I. and Newman, Dianne K. and Weaver, Valerie B. and Kolter, Roberto (1999) Genetic approaches to study of biofilms. In: Biofilms. Methods in enzymology. No.310. Academic Press , San Diego, CA, pp. 91-109. ISBN 9780121822118.

Full text is not posted in this repository. Consult Related URLs below.

Use this Persistent URL to link to this item:


Interest in the study of microbial biofilms has increased greatly in recent years due in large part to the profound impact biofilms have in clinical, industrial, and natural settings. Traditionally, the study of biofilms has been approached from an ecological or engineering perspective, using a combination of classical microbiology and advanced microscopy. We and others have begun to use genetic approaches to understand the development of these complex communities. To begin we must answer the question: What is a biofilm? This definition, by necessity, may be quite broad because it is clear that many organisms can attach to a variety of surfaces under diverse environmental conditions. Therefore, in the context of this article we will operationally define a biofilm as bacteria that are attached to a surface in sufficient numbers to be detected macroscopically.

Item Type:Book Section
Related URLs:
URLURL TypeDescription chapter chapter
Newman, Dianne K.0000-0003-1647-1918
Additional Information:© 1999 Academic Press.
Series Name:Methods in enzymology
Issue or Number:310
Record Number:CaltechAUTHORS:20130506-152623748
Persistent URL:
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:38302
Deposited By: Tony Diaz
Deposited On:19 Sep 2013 19:58
Last Modified:09 Nov 2021 23:36

Repository Staff Only: item control page