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Genetic approaches to study of biofilms

O'Toole, George A. and Pratt, Leslie A. and Watnick, Paula I. and Newman, Dianne K. and Weaver, Valerie B. and Kolter, Roberto (1999) Genetic approaches to study of biofilms. In: Biofilms. Methods in enzymology. No.310. Academic Press , San Diego, CA, pp. 91-109. ISBN 9780121822118. http://resolver.caltech.edu/CaltechAUTHORS:20130506-152623748

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Abstract

Interest in the study of microbial biofilms has increased greatly in recent years due in large part to the profound impact biofilms have in clinical, industrial, and natural settings. Traditionally, the study of biofilms has been approached from an ecological or engineering perspective, using a combination of classical microbiology and advanced microscopy. We and others have begun to use genetic approaches to understand the development of these complex communities. To begin we must answer the question: What is a biofilm? This definition, by necessity, may be quite broad because it is clear that many organisms can attach to a variety of surfaces under diverse environmental conditions. Therefore, in the context of this article we will operationally define a biofilm as bacteria that are attached to a surface in sufficient numbers to be detected macroscopically.


Item Type:Book Section
Related URLs:
URLURL TypeDescription
https://doi.org/10.1016/S0076-6879(99)10008-9DOIBook chapter
http://www.sciencedirect.com/science/article/pii/S0076687999100089?via%3DihubPublisherBook chapter
ORCID:
AuthorORCID
Newman, Dianne K.0000-0003-1647-1918
Additional Information:© 1999 Academic Press.
Record Number:CaltechAUTHORS:20130506-152623748
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:20130506-152623748
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:38302
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:19 Sep 2013 19:58
Last Modified:24 Oct 2017 21:47

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