Epstein, Richard H. and Bolle, Antoinette and Steinberg, Charles M. (2012) Amber Mutants of Bacteriophage T4D: Their Isolation and Genetic Characterization. Genetics, 190 (3). pp. 833-840. ISSN 0016-6731. doi:10.1534/genetics.112.138438. https://resolver.caltech.edu/CaltechAUTHORS:20130513-153611678
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Abstract
We have isolated a large number of mutants of bacteriophage T4D that are unable to form plaques on strain B of Escherichia coli, but are able to grow (nearly) normally on some other strains of E. coli, in particular strain CR63. These mutants, designated amber (am), have been characterized by complementation tests, by genetic crosses, and by their response to chemical mutagens. It is concluded that a particular subclass of base substitution mutations may give rise to amber mutants and that such mutants occur in many genes, which are widely distributed over the T4 genome.
Item Type: | Article | ||||||||||||
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Additional Information: | © 2012 Genetics Society of America. This work was supported by the U.S. Public Health Service (grant E 4267) and by a U.S. Public Health Postdoctoral grant (RG-6965). | ||||||||||||
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Issue or Number: | 3 | ||||||||||||
DOI: | 10.1534/genetics.112.138438 | ||||||||||||
Record Number: | CaltechAUTHORS:20130513-153611678 | ||||||||||||
Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20130513-153611678 | ||||||||||||
Official Citation: | Amber Mutants of Bacteriophage T4D: Their Isolation and Genetic Characterization Richard H. Epstein, Antoinette Bolle, and Charles M. Steinberg Genetics March 2012 190:831-840 | ||||||||||||
Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | ||||||||||||
ID Code: | 38473 | ||||||||||||
Collection: | CaltechAUTHORS | ||||||||||||
Deposited By: | Jason Perez | ||||||||||||
Deposited On: | 13 May 2013 22:56 | ||||||||||||
Last Modified: | 09 Nov 2021 23:37 |
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