CaltechAUTHORS
  A Caltech Library Service

Natural Products as Inspiration for Reaction Development: Catalytic Enantioselective Decarboxylative Reactions of Prochiral Enolate Equivalents

Behenna, Douglas C. and Stoltz, Brian M. (2012) Natural Products as Inspiration for Reaction Development: Catalytic Enantioselective Decarboxylative Reactions of Prochiral Enolate Equivalents. In: Inventing reactions. Topics in organometallic chemistry. No.44. Springer-Verlag , Berlin, pp. 281-314. ISBN 978-3-642-34285-1. https://resolver.caltech.edu/CaltechAUTHORS:20130516-140126410

Full text is not posted in this repository. Consult Related URLs below.

Use this Persistent URL to link to this item: https://resolver.caltech.edu/CaltechAUTHORS:20130516-140126410

Abstract

This account describes the circumstances leading to our group's innovations in the area of decarboxylative asymmetric allylic alkylation reactions and the initial discovery of palladium phosphinooxazoline complexes as efficient enantioselective catalysts. This chapter also chronicles the growth of the methodology to include several substrate classes, the expansion of the project into several other reaction manifolds, and the use of these reactions in natural product synthesis. Finally, important contributions from other research groups involving related methods or products similar to the α-quaternary products that are the focus of our studies, as well as future directions for asymmetric alkylation reactions, are discussed.


Item Type:Book Section
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1007/3418_2012_49DOIArticle
http://link.springer.com/chapter/10.1007%2F3418_2012_49PublisherArticle
ORCID:
AuthorORCID
Stoltz, Brian M.0000-0001-9837-1528
Additional Information:© 2013 Springer-Verlag Berlin Heidelberg. Published online: 18 August 2012.
Subject Keywords:Allylic alkylation; Asymmetric catalysis; Decarboxylation; Enolate α-alkylation; Palladium catalysis; PHOX ligands; Quaternary stereocenters
Series Name:Topics in organometallic chemistry
Issue or Number:44
Record Number:CaltechAUTHORS:20130516-140126410
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20130516-140126410
Official Citation:Behenna, D. and B. Stoltz (2013). Natural Products as Inspiration for Reaction Development: Catalytic Enantioselective Decarboxylative Reactions of Prochiral Enolate Equivalents. Inventing Reactions. L. J. Gooßen, Springer Berlin Heidelberg. 44: 281-314.
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:38547
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:05 Jun 2013 18:29
Last Modified:03 Oct 2019 04:58

Repository Staff Only: item control page