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A New Software Package for Predictive Gene Regulatory Network Modeling and Redesign

Faure, Emmanuel and Peter, Isabelle S. and Davidson, Eric H. (2013) A New Software Package for Predictive Gene Regulatory Network Modeling and Redesign. Journal of Computational Biology, 20 (6). pp. 419-423. ISSN 1066-5277. PMCID PMC3667423. doi:10.1089/cmb.2012.0297. https://resolver.caltech.edu/CaltechAUTHORS:20130708-130927897

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Abstract

The efficacy of a newly created software package for predictive modeling of developmental gene regulatory networks (GRNs) has recently been demonstrated (Peter et al., 2012). The program GeNeTool computes spatial gene expression patterns based on GRN interactions and thereby allows the direct comparison of predicted and observed spatial expression patterns. GeNeTool also permits in silico exploration of both cis- and trans- perturbations of GRN interactions. Here, we present this program, review briefly its major features and applications, and provide a detailed and accessible tutorial.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1089/cmb.2012.0297DOIArticle
http://online.liebertpub.com/doi/abs/10.1089/cmb.2012.0297PublisherArticle
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667423/PubMed CentralArticle
ORCID:
AuthorORCID
Peter, Isabelle S.0000-0003-3685-3147
Additional Information:© 2013 Mary Ann Liebert, Inc. Published in Volume: 20 Issue 6: May 29, 2013; Online Ahead of Print: April 24, 2013.
Subject Keywords:artificial life; gene networks; genetic analysis; recognition of genes; regulatory elements
Issue or Number:6
PubMed Central ID:PMC3667423
DOI:10.1089/cmb.2012.0297
Record Number:CaltechAUTHORS:20130708-130927897
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20130708-130927897
Official Citation:Emmanuel Faure, Isabelle S. Peter, and Eric H. Davidson. Journal of Computational Biology. June 2013, 20(6): 419-423. doi:10.1089/cmb.2012.0297.
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:39249
Collection:CaltechAUTHORS
Deposited By: Jason Perez
Deposited On:09 Jul 2013 14:06
Last Modified:09 Nov 2021 23:43

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