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The Neural Representation of Unexpected Uncertainty during Value-Based Decision Making

Payzan-LeNestour, Elise and Dunne, Simon and Bossaerts, Peter and O'Doherty, John P. (2013) The Neural Representation of Unexpected Uncertainty during Value-Based Decision Making. Neuron, 79 (1). pp. 191-201. ISSN 0896-6273. PMCID PMC4885745. https://resolver.caltech.edu/CaltechAUTHORS:20130815-091302247

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Abstract

Uncertainty is an inherent property of the environment and a central feature of models of decision-making and learning. Theoretical propositions suggest that one form, unexpected uncertainty, may be used to rapidly adapt to changes in the environment, while being influenced by two other forms: risk and estimation uncertainty. While previous studies have reported neural representations of estimation uncertainty and risk, relatively little is known about unexpected uncertainty. Here, participants performed a decision-making task while undergoing functional magnetic resonance imaging (fMRI), which, in combination with a Bayesian model-based analysis, enabled us to separately examine each form of uncertainty examined. We found representations of unexpected uncertainty in multiple cortical areas, as well as the noradrenergic brainstem nucleus locus coeruleus. Other unique cortical regions were found to encode risk, estimation uncertainty, and learning rate. Collectively, these findings support theoretical models in which several formally separable uncertainty computations determine the speed of learning.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1016/j.neuron.2013.04.037 DOIArticle
http://www.sciencedirect.com/science/article/pii/S0896627313003681PublisherArticle
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4885745PubMed CentralArticle
ORCID:
AuthorORCID
Bossaerts, Peter0000-0003-2308-2603
Additional Information:© 2013 Elsevier Inc. Accepted: April 26, 2013; Published: July 10, 2013. This work was supported by the Science Foundation Ireland grant 08/IN.1/B1844 and a European Research Council grant (to J.O.D). P.B. and E.P.L.N. acknowledge the support of the Swiss Finance Institute to the Ecole Polytechnique Fédérale Lausanne.
Funders:
Funding AgencyGrant Number
Science Foundation, Ireland08/IN.1/B1844
European Research Council (ERC)UNSPECIFIED
Swiss Finance InstituteUNSPECIFIED
Issue or Number:1
PubMed Central ID:PMC4885745
Record Number:CaltechAUTHORS:20130815-091302247
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20130815-091302247
Official Citation:Elise Payzan-LeNestour, Simon Dunne, Peter Bossaerts, John P. O’Doherty, The Neural Representation of Unexpected Uncertainty during Value-Based Decision Making, Neuron, Volume 79, Issue 1, 10 July 2013, Pages 191-201, ISSN 0896-6273, http://dx.doi.org/10.1016/j.neuron.2013.04.037.
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:39939
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:19 Aug 2013 18:28
Last Modified:03 Oct 2019 05:12

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