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Integrated microfluidic systems

Ismagilov, Rustem F. (2003) Integrated microfluidic systems. Angewandte Chemie International Edition, 42 (35). pp. 4130-4132. ISSN 1433-7851. doi:10.1002/anie.200301660.

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Microchips: Multistep reactions may be catalyzed by enzymes immobilized on microbeads trapped inside microfluidic channels. Large integrated microfluidic circuits can be created by using multilayer soft lithography in poly(dimethylsiloxane). These circuits (see schematic representation) can be used to perform hundreds of different reactions simultaneously, and can be applied to a range of problems, from enzymatic assays to crystallization of proteins.

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Ismagilov, Rustem F.0000-0002-3680-4399
Additional Information:Copyright © 2003 WILEY-VCH. Original figures were generously provided by Prof. Richard Crooks and by Prof. Stephen Quake. Support by ONR is gratefully acknowledged.
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Subject Keywords:analytical methods, enzymes, microfluidics, microreactors, protein structures
Issue or Number:35
Record Number:CaltechAUTHORS:20130821-160719583
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Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:40798
Deposited By: Whitney Barlow
Deposited On:28 Aug 2013 20:55
Last Modified:10 Nov 2021 00:08

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