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Pressure-driven laminar flow in tangential microchannels: an elastomeric microfluidic switch

Ismagilov, Rustem F. and Rosmarin, David and Kenis, Paul J. A. and Chiu, Daniel T. and Zhang, Wendy and Stone, Howard A. and Whitesides, George M. (2001) Pressure-driven laminar flow in tangential microchannels: an elastomeric microfluidic switch. Analytical Chemistry, 73 (19). pp. 4682-4687. ISSN 0003-2700. doi:10.1021/ac010374q.

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This paper describes laminar fluid flow through a three- dimensional elastomeric microstructure formed by two microfluidic channels, fabricated in layers that contact one another face-to-face (typically at a 90 degrees angle), with the fluid flows in tangential contact. There are two ways to control fluid flow through these tangentially connected microchannels. First, the flow profiles through the crossings are sensitive to the aspect ratio of the channels; the flow can be controlled by applying external pressure and changing this aspect ratio. Second, the flow direction of an individual laminar stream in multiphase laminar flow depends on the lateral position of the stream within the channel; this position can be controlled by injecting additional streams of fluid into the channel. We describe two microfluidic switches based on these two ways for controlling fluid flow through tangential microchannels and present theoretical arguments that explain the observed dependence of the flow profiles on the aspect ratio of the channels.

Item Type:Article
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URLURL TypeDescription
Ismagilov, Rustem F.0000-0002-3680-4399
Whitesides, George M.0000-0001-9451-2442
Additional Information:Copyright © 2001 American Chemical Society. Published In Issue: October 01, 2001. Received for review April 2, 2001. Accepted July 8, 2001. This work was supported by DARPA and NSF ECS-0004030 and ECS-9729405. We thank Jacqueline Ashmore (Harvard) for helpful discussions.
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Subject Keywords:systems; fabrication; poly(dimethylsiloxane); networks; pdms
Issue or Number:19
Record Number:CaltechAUTHORS:20130821-160720235
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Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:40802
Deposited By: Whitney Barlow
Deposited On:23 Aug 2013 22:11
Last Modified:10 Nov 2021 00:08

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