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Structure/function interface with sequential shortening of basal and apical components of the myocardial band

Buckberg, Gerald D. and Castellá, Manuel and Gharib, Morteza and Saleh, Saleh (2006) Structure/function interface with sequential shortening of basal and apical components of the myocardial band. European Journal of Cardio-Thoracic Surgery, 29 (S1). S75-S97. ISSN 1010-7940 . https://resolver.caltech.edu/CaltechAUTHORS:20130911-080329547

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Abstract

Objective: To study the sequential shortening of Torrent-Guasp's ‘rope-heart model’ of the muscular band, and analyze the structure–function relationship of basal loop wrapping the outer right and left ventricles, around the inner helical apical loop containing reciprocal descending and ascending spiral segments. Methods: In 24 pigs (27–82 kg), temporal shortening by sonomicrometer crystals was recorded. The ECG evaluated rhythm, and Millar pressure transducers measured intraventricular pressure and dP/dt. Results: The predominant shortening sequence proceeded from right to left in basal loop, then down the descending and up the ascending apical loop segments. In muscle surrounded by the basal loop, epicardial muscle predominantly shortened before endocardial muscle. Crystal location defined underlying contractile trajectory; transverse in basal versus oblique in apical loop, subendocardial in descending and subepicardial in ascending segments. Mean shortening fraction average 18 ± 3%, with endocardial exceeding epicardial shortening by 5 ± 1%. Ascending segment crystal displacement followed descending shortening by 82 ± 23 ms, and finished 92 ± 33 ms after descending shortening stops, causing active systolic shortening to suction venous return; isovolumetric relaxation was absent. Conclusions: Shortening sequence followed the rope-like myocardial band model to contradict traditional thinking. Epicardial muscle shortened before endocardial papillary muscle despite early endocardial activation, and suction filling follows active systolic unopposed ascending segment shortening during the ‘isovolumetric relaxation’ phase.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1016/j.ejcts.2006.02.065 DOIArticle
http://ejcts.oxfordjournals.org/content/29/Supplement_1/S75PublisherArticle
Additional Information:© 2006 Published by Elsevier B.V. Received 17 February 2006; accepted 27 February 2006.
Group:GALCIT
Subject Keywords:Helical ventricular myocardial band; Isovolumetric contraction and relaxation; Sonomicrometer crystals; Systolic ventricular filling
Issue or Number:S1
Record Number:CaltechAUTHORS:20130911-080329547
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20130911-080329547
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:41228
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:11 Sep 2013 22:05
Last Modified:03 Oct 2019 05:47

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