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The Effects of Broadly Neutralizing Antibodies in Experimental HCV Infection

de Jong, Y. P. and Dorner, M. and Balazs, A. B. and Robbins, J. B. and Labitt, R. N. and Donovan, B. M. and Krishnan, A. and Charlton, M. and Chiriboga, L. and Burton, D. R. and Rice, C. M. and Baltimore, D. and Law, M. and Ploss, A. (2013) The Effects of Broadly Neutralizing Antibodies in Experimental HCV Infection. Journal of Hepatology, 58 . S466-S467. ISSN 0168-8278. https://resolver.caltech.edu/CaltechAUTHORS:20130916-154115267

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Abstract

Hepatitis C virus (HCV) infection is the leading indication for liver transplantation in the US. The graft is universally infected after transplantation, and this typically results in accelerated fibrosis progression. Current HCV therapies have poor efficacy and tolerability in the challenging pre- and posttransplant populations. Alternative pre- and post-transplantation measures are needed to prevent graft infection. One potential strategy to prevent such infection is the administration of potent broadly neutralizing antibodies (bnAbs).


Item Type:Article
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http://download.journals.elsevierhealth.com/pdfs/journals/0168-8278/PIIS0168827813611472.pdfPublisherArticle
ORCID:
AuthorORCID
Baltimore, D.0000-0001-8723-8190
Additional Information:© 2013 European Association for the Study of the Liver.
Record Number:CaltechAUTHORS:20130916-154115267
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20130916-154115267
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:41350
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:17 Sep 2013 20:00
Last Modified:03 Oct 2019 05:48

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