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Natural Product Synthesis: A Platform for Chemical Discovery

Reisman, Sarah E. (2013) Natural Product Synthesis: A Platform for Chemical Discovery. In: 68th Northwest Regional Meeting of the American Chemical Society, July 21-24, 2013, Corvallis, OR.

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The overarching goal of our research is to discover, develop, and study new chem. reactions within the context of natural product total synthesis. The chem. synthesis of natural products enables the study of their biol. properties, and can provide access to synthetic derivs. with improved therapeutic properties or that can serve as mechanistic probes. As importantly, these synthetic undertakings serve to drive innovation in, and deepen our fundamental understanding of, org. and organometallic chem. Our lab. has ongoing research programs targeting the chem. syntheses of several natural products, including members of the epidithiodiketopiperazines, the ent-kauranoids, and the acutumine alkaloids. The densely packed arrays of heteroatoms and stereogenic centers that constitute these polycyclic targets challenge the limits of current synthetic methodol. This seminar will describe our latest progress in both our methodol. and target-directed synthesis endeavors.

Item Type:Conference or Workshop Item (Paper)
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Reisman, Sarah E.0000-0001-8244-9300
Additional Information:© 2013 American Chemical Society
Record Number:CaltechAUTHORS:20131009-085028526
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Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:41783
Deposited By: Tony Diaz
Deposited On:09 Oct 2013 16:37
Last Modified:03 Oct 2019 05:52

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