Developments in the synthesis of small and large molecules using olefin metathesis catalysts

Abstract

Olefin metathesis is an established technique for making and breaking carbon-carbon double bonds, and has been adapted in applications that range from total synthesis to high performance plastics. Over the past several decades, efforts have been directed toward the development of catalysts that display enhanced functional group tolerance or increased selectivity as compared to their precursors, or facilitate access to small and macromols. with unique structures and functions. In this presentation, we will describe previous and recent efforts aimed at designing and accessing new classes of olefin metathesis catalysts as well as our efforts toward using catalysts in hand in various applications.