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Astrogenomics: big data, old problems, old solutions?

Golden, Aaron and Djorgovski, S. George and Greally, John M. (2013) Astrogenomics: big data, old problems, old solutions? Genome Biology, 14 . Art. No. 129. ISSN 1465-6906. PMCID PMC4053852. doi:10.1186/gb-2013-14-8-129. https://resolver.caltech.edu/CaltechAUTHORS:20131107-153839658

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Abstract

The ominous warnings of a data deluge in the life sciences from high-throughput DNA sequencing data are being supplanted by a second deluge, of clichés bemoaning our collective scientific fate unless we address the genomic data tsunami. It is imperative that we explore the many facets of the genome, not just sequence but also transcriptional and epigenetic variability, integrating these observations in order to attain a genuine understanding of how genes function, towards a goal of genomics-based personalized medicine. Determining any individual's genomic properties requires comparison to many others, sifting out the specific from the trends, requiring access to the many in order to yield information relevant to the few. This is the central big data challenge in genomics that still requires some sort of resolution. Is there a practical, feasible way of directly connecting the scientific community to this data universe?


Item Type:Article
Related URLs:
URLURL TypeDescription
http://arxiv.org/abs/1308.3277arXivDiscussion Paper
http://genomebiology.com/content/14/8/129PublisherArticle
http://dx.doi.org/10.1186/gb-2013-14-8-129DOIArticle
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053852/PubMed CentralArticle
ORCID:
AuthorORCID
Golden, Aaron0000-0002-8599-2031
Djorgovski, S. George0000-0002-0603-3087
Additional Information:© 2013 BioMed Central Ltd. Published: 13 August 2013.
PubMed Central ID:PMC4053852
DOI:10.1186/gb-2013-14-8-129
Record Number:CaltechAUTHORS:20131107-153839658
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20131107-153839658
Official Citation:Golden A, et al.: Astrogenomics: big data, old problems, old solutions? Genome Biology 2013, 14:129
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:42323
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:08 Nov 2013 00:55
Last Modified:10 Nov 2021 16:21

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