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Computational Analysis of Anti-HIV-1 Antibody Neutralization Panel Data to Identify Potential Functional Epitope Residues

West, A. P., Jr. and Scharf, L. and Horwitz, J. and Klein, F. and Nussenzweig, M. C. and Bjorkman, P. J. (2013) Computational Analysis of Anti-HIV-1 Antibody Neutralization Panel Data to Identify Potential Functional Epitope Residues. AIDS Research and Human Retroviruses, 29 (11). A170. ISSN 0889-2229. https://resolver.caltech.edu/CaltechAUTHORS:20131122-104048690

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Abstract

Advances in single cell antibody cloning methods have led to the identification of a variety of broadly neutralizing anti-HIV-1 antibodies. Initial characterization of these antibodies often involves measurement of their neutralization activity against a panel of viruses, but such experiments do not generally lead to conclusive identification of an antibody’s epitope.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1089/aid.2013.1500DOIAbstracts
http://online.liebertpub.com/doi/abs/10.1089/aid.2013.1500PublisherAbstracts
ORCID:
AuthorORCID
Nussenzweig, M. C.0000-0003-0592-8564
Bjorkman, P. J.0000-0002-2277-3990
Additional Information:© 2013 Mary Ann Liebert, Inc. publishers. Published in Volume: 29 Issue 11: October 24, 2013. Online Ahead of Print: October 10, 2013.
Issue or Number:11
Record Number:CaltechAUTHORS:20131122-104048690
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20131122-104048690
Official Citation:AIDS Research and Human Retroviruses. November 2013, 29(11): A-1-A-208. doi:10.1089/aid.2013.1500
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:42653
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:24 Nov 2013 00:41
Last Modified:03 Oct 2019 06:00

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