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Analysis of the Human Macula by Confocal Laser Tomography

Bartsch, Dirk-Uwe and Bille, Josef F. and Dreher, Andreas W. and Intaglietta, Marcos and Gharib, Morteza and Freeman, William R. (1990) Analysis of the Human Macula by Confocal Laser Tomography. In: Scanning laser ophthalmoscopy and tomography. Quintessenz , München, Germany, pp. 215-223. ISBN 9783928036016.

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Laser scanning tomography was used to study the surface of the diseased and normal macula in the human eye. The confocal arrangement of the laser tomographic scanner permits the examination of the retinal topography in the axis perpendicular to the retinal surface. It was found that the normal macular surface as seen in histological preparations can be reconstructed in humans with the laser tomographic scanner. A polarization pattern can be observed in the area of Henle's fiber layer. We were able to reproducibly image a brush-like pattern with the circular polarized laser light in healthy eyes of 25 patients. In contrast, we did not observe it in eyes with structural changes of the macular tissue, indicating that loss of the brush-like phenomena may be an early and sensitive indication of macular diseases. In diseased eyes we were able to assess structural abnormalities, such as macular holes, laser scars, macular branch vein occlusion and macular edema. The laser tomographic scanner offers a new method to determine the topography of the internal limiting membrane in the macular area.

Item Type:Book Section
Gharib, Morteza0000-0002-2204-9302
Freeman, William R.0000-0003-3559-5270
Additional Information:© 1990 Quintessenz Verlags-GmbH, München.
Record Number:CaltechAUTHORS:20131209-081205363
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Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:42889
Deposited By: Tony Diaz
Deposited On:11 Dec 2013 21:32
Last Modified:09 Mar 2020 13:18

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