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Quantitative phase imaging via Fourier ptychographic microscopy

Ou, Xiaoze and Horstmeyer, Roarke and Yang, Changhuei and Zheng, Guoan (2013) Quantitative phase imaging via Fourier ptychographic microscopy. Optics Letters, 38 (22). pp. 4845-4848. ISSN 0146-9592. PMCID PMC4277232.

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Fourier ptychographic microscopy (FPM) is a recently developed imaging modality that uses angularly varying illumination to extend a system’s performance beyond the limit defined by its optical components. The FPM technique applies a novel phase-retrieval procedure to achieve resolution enhancement and complex image recovery. In this Letter, we compare FPM data to theoretical prediction and phase-shifting digital holography measurement to show that its acquired phase maps are quantitative and artifact-free. We additionally explore the relationship between the achievable spatial and optical thickness resolution offered by a reconstructed FPM phase image. We conclude by demonstrating enhanced visualization and the collection of otherwise unobservable sample information using FPM’s quantitative phase.

Item Type:Article
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URLURL TypeDescription Paper DOIArticle CentralArticle
Horstmeyer, Roarke0000-0002-2480-9141
Yang, Changhuei0000-0001-8791-0354
Additional Information:© 2013 Optical Society of America. Received August 1, 2013; revised September 26, 2013; accepted October 15, 2013; posted October 18, 2013 (Doc. ID 195056); published November 14, 2013. This work was supported by a grant from the National Institutes of Health (NIH) (NIH 1R01AI096226-01).
Funding AgencyGrant Number
Issue or Number:22
Classification Code:OCIS codes: (180.0180) Microscopy; (100.5070) Phase retrieval; (120.5050) Phase measurement
PubMed Central ID:PMC4277232
Record Number:CaltechAUTHORS:20131224-100217865
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Official Citation:X. Ou, R. Horstmeyer, C. Yang, and G. Zheng, "Quantitative phase imaging via Fourier ptychographic microscopy," Opt. Lett. 38, 4845-4848 (2013).
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:43164
Deposited By: Tony Diaz
Deposited On:24 Dec 2013 18:54
Last Modified:09 Mar 2020 13:19

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