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Self-Assembly of Globular-Protein-Containing Block Copolymers

Olsen, Bradley D. (2013) Self-Assembly of Globular-Protein-Containing Block Copolymers. Macromolecular Chemistry and Physics, 214 (15). pp. 1659-1668. ISSN 1022-1352. http://resolver.caltech.edu/CaltechAUTHORS:20140103-144745450

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Abstract

Self-assembly has emerged as a powerful approach to control nanostructure in materials containing globular proteins, both through templated self-assembly and direct self-assembly of globular protein-polymer conjugates or fusion proteins. The folded structures of globular proteins that are critical to their function introduce complex shapes and interactions into block copolymers that significantly alter the physics of self-assembly. This article discusses the different methods for controlling the nanostructure of globular proteins using block copolymers, highlighting efforts at understanding the physics of self-assembly in concentrated solution and solid-state bioconjugate copolymers.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1002/macp.201300235 DOIArticle
http://onlinelibrary.wiley.com/doi/10.1002/macp.201300235/abstractPublisherArticle
Additional Information:© 2013 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim. March 6, 2013 ; Revised: April 26, 2013 ; Published online: July 25, 2013. This work was supported by the Department of Energy Office of Basic Energy Sciences (award number DE-SC0007106). B.D.O. thanks Dongsook Chang and Chris Lam for helpful conversations.
Funders:
Funding AgencyGrant Number
Department of Energy (DOE) Office of Basic Energy Sciences DE-SC0007106
Subject Keywords:bioconjugates; block copolymers; nanostructures; proteins; self-assembly
Record Number:CaltechAUTHORS:20140103-144745450
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:20140103-144745450
Official Citation:Olsen, B. D. (2013), Self-Assembly of Globular-Protein-Containing Block Copolymers. Macromol. Chem. Phys., 214: 1659–1668. doi: 10.1002/macp.201300235
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:43209
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:04 Jan 2014 00:40
Last Modified:04 Jan 2014 00:40

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