Kulikov, Oleg V. and Thompson, Sam and Xu, Hai and Incarvito, Christopher D. and Scott, Richard T. and Saraogi, Ishu and Nevola, Laura and Hamilton, Andrew D. (2013) Design and synthesis of oligoamide-based double α-helix mimetics. In: 246th ACS National Meeting & Exposition, Sept. 8-12, 2013, Indianapolis, IN. https://resolver.caltech.edu/CaltechAUTHORS:20140213-150022614
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Abstract
An extensive series of bis-oligobenzamides and bisoligopyridylamides were efficiently prepd. and studied by X-ray anal. and computation. A modular synthesis gave double α-helix mimics bearing between two and ten branched side-chains. The inter-helix angle and distance can be tuned by varying the length and rigidity of spacer, thus reproducing the recognition domains of a range of super-secondary structures.
| Item Type: | Conference or Workshop Item (Paper) | ||||||
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| Additional Information: | © 2013 American Chemical Society. | ||||||
| Record Number: | CaltechAUTHORS:20140213-150022614 | ||||||
| Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20140213-150022614 | ||||||
| Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | ||||||
| ID Code: | 43822 | ||||||
| Collection: | CaltechAUTHORS | ||||||
| Deposited By: | Tony Diaz | ||||||
| Deposited On: | 25 Mar 2014 17:38 | ||||||
| Last Modified: | 03 Oct 2019 06:11 |
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