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The specifity of serological precipitation

Lanni, Frank (1946) The specifity of serological precipitation. Journal of Experimental Medicine, 84 (2). pp. 167-180. ISSN 0022-1007. doi:10.1084/jem.84.2.167.

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Precipitative mixing experiments have been conducted with the aid of a turbidimeter and a darkfield microscope. The results of these experiments, correlated with observations of macroscopic features, indicate that serological precipitation is largely governed by a highly specific mechanism except in the terminal period, when the operation of non-specific forces becomes apparent. The findings are used as the basis for a new description of precipitation in terms of the formation and aggregation of elementary particles of specific precipitate, called seromicrons.

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Additional Information:© 1946, by The Rockefeller Institute for Medical Research New York. (Received for publication, April 23, 1946) The present investigation was aided in part by a grant from The Rockefeller Foundation for research in immunochemistry. It is a pleasure to acknowledge the inspiration and guidance received from Professor Linus Pauling, Professor Dan H. Campbell, and Professor Verner Schomaker. Predoctoral Fellow of the National Research Council. Contribution No. 1061 from the Gates and Crellin Laboratories of Chemistry, California Institute of Technology, Pasadena
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Rockefeller FoundationUNSPECIFIED
National Research CouncilUNSPECIFIED
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Gates and Crellin Laboratories of Chemistry1061
Issue or Number:2
Record Number:CaltechAUTHORS:LANjem46
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Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:4417
Deposited By: Archive Administrator
Deposited On:22 Aug 2006
Last Modified:08 Nov 2021 20:17

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