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Harnessing chemistry to discover new roles for carbohydrates in neurobiology and cancer

Hsieh-Wilson, Linda C. (2014) Harnessing chemistry to discover new roles for carbohydrates in neurobiology and cancer. In: 247th ACS National Meeting & Exposition, March 16-20, 2014, Dallas, TX.

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Carbohydrates comprise one of the largest and most diverse collections of biol. active mols., and they participate in nearly every aspect of biol. However, relative to their macromol. peers (i.e., proteins and nucleic acids), carbohydrates remain relatively unexplored, and their structure-function relationships are still poorly understood. Several of the fundamental challenges inherent in studying carbohydrates include: (1) their chem. complexity; (2) the lack of efficient and sensitive anal. methods for their detection and quantification; and (3) their complex chem. synthesis and biosynthesis. We will describe the development of chem. approaches to overcome these fundamental challenges and how the principles and tools of chem. can be used to uncover new functions for carbohydrates and their assocd. proteins in neurobiol. and cancer.

Item Type:Conference or Workshop Item (Paper)
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Hsieh-Wilson, Linda C.0000-0001-5661-1714
Additional Information:© 2014 American Chemical Society.
Record Number:CaltechAUTHORS:20140424-104655243
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Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:45188
Deposited By: Tony Diaz
Deposited On:24 Apr 2014 22:19
Last Modified:03 Oct 2019 06:27

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