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Engineering synthetic medea-based and threshold-dependent underdominance-based gene drive systems in mosquitos

Akbari, Omar and Marshall, John and Antoshechkin, Igor and Matzen, Kelly and Papathanos, Philippos and Kennedy, Katie and Ward, Catherine and Cheng, Chun-Hong and Guo, Ming and Hay, Bruce A. (2013) Engineering synthetic medea-based and threshold-dependent underdominance-based gene drive systems in mosquitos. Pathogens and Global Health, 107 (8). p. 442. ISSN 2047-7724. doi:10.1179/2047772413Z.000000000160. https://resolver.caltech.edu/CaltechAUTHORS:20140603-105237691

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Abstract

Mosquito population replacement requires gene drive mechanisms in order to spread linked genes, mediating disease refractoriness, through wild populations. Medea is predicted to be a low threshold gene drive mechanism, able to spread from low initial frequency.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://www.maneyonline.com/doi/abs/10.1179/2047772413Z.000000000160PublisherConference Proceedings
http://dx.doi.org/10.1179/2047772413Z.000000000160DOIConference Proceedings
ORCID:
AuthorORCID
Akbari, Omar0000-0002-6853-9884
Antoshechkin, Igor0000-0002-9934-3040
Additional Information:© 2013 Maney Publishing.
Issue or Number:8
DOI:10.1179/2047772413Z.000000000160
Record Number:CaltechAUTHORS:20140603-105237691
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20140603-105237691
Official Citation:"EMBO Conference on Molecular and Population Biology of Mosquitoes and Other Disease Vectors: From Basic Vector Biology to Disease Control." Pathogens and Global Health, 107(8), pp. 400–457
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:46048
Collection:CaltechAUTHORS
Deposited By: Ruth Sustaita
Deposited On:03 Jun 2014 20:29
Last Modified:10 Nov 2021 17:20

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