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Engineering Recombinant AAV Vectors for More Efficient and Restricted Gene Expression in the CNS after Systemic Administration

Deverman, Benjamin E. and Simpson, Bryan and Pravdo, Piers and Banerjee, Abhik and Patterson, Paul H. (2014) Engineering Recombinant AAV Vectors for More Efficient and Restricted Gene Expression in the CNS after Systemic Administration. Molecular Therapy, 22 (S1). S118. ISSN 1525-0016. https://resolver.caltech.edu/CaltechAUTHORS:20140717-151830932

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Abstract

We previously demonstrated that delivery of the cytokine leukemia inhibitory factor (LIF) to the brain by recombinant adenovirus enhances oligodendrocyte progenitor cell proliferation and remyelination in a mouse model of multiple sclerosis (MS).


Item Type:Article
Related URLs:
URLURL TypeDescription
http://www.nature.com/mt/journal/v22/n1s/index.htmlPublisherArticle
http://www.abstracts2view.com/asgct/view.php?nu=ASGCT14L1_307PublisherArticle
http://dx.doi.org/10.1038/mt.2014.66DOIArticle
Additional Information:© 2014 American Society of Gene & Cell Therapy.
Issue or Number:S1
Record Number:CaltechAUTHORS:20140717-151830932
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20140717-151830932
Official Citation:Mol Ther 22: S307-S320; doi:10.1038/mt.2014.66
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:47306
Collection:CaltechAUTHORS
Deposited By: Ruth Sustaita
Deposited On:17 Jul 2014 23:59
Last Modified:03 Oct 2019 06:52

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