Transition metal complexes supported by (8-quinolynyl)amido ligands

Abstract

Our program is targeting the preparation of reactive transition metal complexes suitable for the activation and functionalization of small molecule substrates. As part of this effort we have prepared a series of anionic, chelating amido ligands derived from 8-aminoquinoline utilizing Pd-coupling methods. Thus far, a host of Group VIII, IX, and X transition metal systems has been developed from the parent BQA (BQA = bis(8-quinolynyl)amide) ligand, such as those examples depicted below. The preparative chemistry enabling access to these and several second generation systems will be discussed, in addition to their unfolding reaction chemistry.