Hollmann, Joseph L. and Horstmeyer, Roarke and Yang, Changhuei and DiMarzio, Charles A. (2014) Diffusion model for ultrasound-modulated light. Journal of Biomedical Optics, 19 (3). Art. No. 035005. ISSN 1083-3668. https://resolver.caltech.edu/CaltechAUTHORS:20140731-094446383
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Abstract
Researchers use ultrasound (US) to modulate diffusive light in a highly scattering medium like tissue. This paper analyzes the US–optical interaction in the scattering medium and derives an expression for the US-modulated optical radiance. The diffusion approximation to the radiative transport equation is employed to develop a Green’s function for US-modulated light. The predicted modulated fluence and flux are verified using finite-difference time-domain simulations. The Green’s function is then utilized to illustrate the modulated reflectance as the US–optical interaction increases in depth. The intent of this paper is to focus on high US frequencies necessary for high-resolution imaging because they are of interest for applications such as phase conjugation.
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Additional Information: | © 2014 Society of Photo-Optical Instrumentation Engineers (SPIE). Paper 130709RR received Sep. 29, 2013; revised manuscript received Jan. 29, 2014; accepted for publication Jan. 30, 2014; published online Mar. 17, 2014. J. Hollmann acknowledges support from the National Science Foundation Graduate Fellowship awarded through the East Asia and Pacific Summer Institutes for U.S. Graduate Students. R. Horstmeyer acknowledges support from the National Defense Science and Engineering Graduate fellowship awarded through the Air Force Office of Scientific Research. | ||||||||||
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Subject Keywords: | ultrasound modulation of light; diffusion; finite-difference time-domain | ||||||||||
Issue or Number: | 3 | ||||||||||
Record Number: | CaltechAUTHORS:20140731-094446383 | ||||||||||
Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20140731-094446383 | ||||||||||
Official Citation: | Hollmann JL, Horstmeyer R, Yang C, DiMarzio CA; Diffusion model for ultrasound-modulated light. J. Biomed. Opt. 0001;19(3):035005. doi:10.1117/1.JBO.19.3.035005 | ||||||||||
Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | ||||||||||
ID Code: | 47700 | ||||||||||
Collection: | CaltechAUTHORS | ||||||||||
Deposited By: | Tony Diaz | ||||||||||
Deposited On: | 31 Jul 2014 18:50 | ||||||||||
Last Modified: | 03 Oct 2019 06:56 |
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