Garg, Neil K. and Woodroofe, Carolyn C. and Lacenere, Christopher J. and Quake, Stephen R. and Stoltz, Brian M. (2005) A ligand-free solid-supported system for Sonogashira couplings: applications in nucleoside chemistry. Chemical Communications, 2005 (36). pp. 4551-4553. ISSN 1359-7345. doi:10.1039/b505737j. https://resolver.caltech.edu/CaltechAUTHORS:GARcc05
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Abstract
A mild heterogeneous, ligand-free protocol for Sonogashira and Heck couplings has been developed and used to access several biologically important deoxynucleoside derivatives in a facile manner.
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| Additional Information: | © The Royal Society of Chemistry 2005 Received (in Bloomington, IN, USA) 25th April 2005, Accepted 16th May 2005. First published on the web 12th August 2005 The authors thank the NIH (R01 HG003594), the Rosen Fellowship (for C.J.L.) and the NDSEG (pre-doctoral fellowship to N.K.G.) for financial support. We also thank E. James Petersson for helpful discussions. Experimental details and 1H NMR spectra for all compounds (supplementary information) | ||||||||
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| Subject Keywords: | HECK REACTION; HETEROGENEOUS PALLADIUM; IN-VITRO; CATALYST; PD/C; NUCLEOTIDES; ACETYLENES; CHARCOAL; CARBON; ACIDS | ||||||||
| Issue or Number: | 36 | ||||||||
| DOI: | 10.1039/b505737j | ||||||||
| Record Number: | CaltechAUTHORS:GARcc05 | ||||||||
| Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:GARcc05 | ||||||||
| Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | ||||||||
| ID Code: | 4942 | ||||||||
| Collection: | CaltechAUTHORS | ||||||||
| Deposited By: | Archive Administrator | ||||||||
| Deposited On: | 14 Sep 2006 | ||||||||
| Last Modified: | 08 Nov 2021 20:21 |
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