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The need for a global HIV vaccine enterprise

Klausner, Richard D. and Fauci, Anthony S. and Corey, Lawrence and Nabel, Gary J. and Gayle, Helene and Berkley, Seth and Haynes, Barton F. and Baltimore, David and Collins, Chris and Douglas, R. Gordon and Esparza, Jose and Francis, Donald P. and Ganguly, N. K. and Gerberding, Julie Louise and Johnston, Margaret I. and Kazatchkine, Michel D. and McMichael, Andrew J. and Makgoba, Malegapuru W. and Pantaleo, Giuseppe and Piot, Peter and Shao, Yiming and Tramont, Edmund and Varmus, Harold and Wasserheit, Judith N. (2003) The need for a global HIV vaccine enterprise. Science, 300 (5628). pp. 2036-2039. ISSN 0036-8075.

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A new collaborative model of research is needed to increase resources, to prioritize the R&D agenda of the major public- and private-sector stakeholders, and ultimately to increase the probability and shorten the time to development of effective HIV vaccines for global use. The thrust of our proposal is (i) to increase the scale and organization for solving science problems and developing novel HIV vaccine approaches; (ii) to increase the pace, reduce the overlap, and more systematically explore the elements of and delivery systems for vaccines; (iii) to use common standards for the prompt comparative testing of vaccine candidates; (iv) to expand resources for manufacturing vaccine candidates to speed their use in human trials; and (v) to increase the capacity for international clinical trials and to focus this effort toward quickly measuring the effectiveness of vaccine protection as prototype vaccine candidates are identified.

Item Type:Article
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Baltimore, David0000-0001-8723-8190
Additional Information:© 2003 American Association for the Advancement of Science.
Issue or Number:5628
Record Number:CaltechAUTHORS:20141117-135530827
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Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:51858
Deposited By: Tony Diaz
Deposited On:17 Nov 2014 22:15
Last Modified:03 Oct 2019 07:36

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