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Color sub-pixel resolving optofluidic microscope and its application to blood cell imaging for malaria diagnosis

Lee, Seung Ah and Leitao, Ricardo and Zheng, Guoan and Yang, Samuel and Rodriguez, Ana and Yang, Changhuei (2011) Color sub-pixel resolving optofluidic microscope and its application to blood cell imaging for malaria diagnosis. In: 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011. Curran Associates, Inc. , San Diego, CA, pp. 1947-1949. ISBN 9781618395955. https://resolver.caltech.edu/CaltechAUTHORS:20141125-080704287

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Abstract

We report on the implementation of color sub-pixel resolving optofluidic microscope (SROFM), a high resolution (HR) on-chip imaging system for diagnostic applications in rural regions. With the combination of microfluidics and inexpensive complementary metal oxide semiconductor (CMOS) image sensors, we demonstrate optical resolution of 0.66 µm at the highest acuity. We applied the prototypes to perform color imaging of red blood cells (RBCs) infected with Plasmodium falciparum (P. falciparum), a particularly harmful type of malaria parasites and one of the major causes of death in the developing world.


Item Type:Book Section
Related URLs:
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http://microtasconferences.org/microtas2011/OrganizationConference Website
Additional Information:© 2011 Curran Associates, Inc. We acknowledge funding support from the Gates Foundation.
Funders:
Funding AgencyGrant Number
Bill and Melinda Gates FoundationUNSPECIFIED
Record Number:CaltechAUTHORS:20141125-080704287
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20141125-080704287
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:52120
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:25 Nov 2014 20:44
Last Modified:03 Oct 2019 07:39

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