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Identification of Drosophila V+ hormone of bacterial origin

Tatum, E. L. and Haagen-Smit, A. J. (1941) Identification of Drosophila V+ hormone of bacterial origin. Journal of Biological Chemistry, 140 (2). pp. 575-580. ISSN 0021-9258.

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The substance produced by certain bacteria from ℓ-tryptophane and which possesses v+ hormone activity in Drosophila has been found to be a sucrose ester of ℓ-kynurenine. The ℓ-kynurenine is the essential active portion of the molecule. ℓ-Kynurenine, ℓ-kynurenine sulfate, and the ℓ-kynurenine-sucrose derivative have the same molar activity when tested in Drosophila larvae. This value approximates 12 X 10^6 units per mM.

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Additional Information:Copyright © 1941 by the American Society for Biological Chemists (Received for publication, March 24, 1941) This work was supported in part by funds granted by the Rockefeller Foundation. The authors wish to express their thanks to Dr. Clarence P. Herg, State University of Iowa, Iowa City, for his kindness in supplying the samples of ℓ-kynurenine, d-kynurenine, d-tryptophane, and kynurenic acid used in this investigation.
Issue or Number:2
Record Number:CaltechAUTHORS:TATjbc41
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Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:5213
Deposited By: Archive Administrator
Deposited On:05 Oct 2006
Last Modified:02 Oct 2019 23:20

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