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Behavioral Mutants of Drosophila Isolated by Countercurrent Distribution

Benzer, Seymour (1967) Behavioral Mutants of Drosophila Isolated by Countercurrent Distribution. Proceedings of the National Academy of Sciences of the United States of America, 58 (3). pp. 1112-1119. ISSN 0027-8424. PMCID PMC335755. http://resolver.caltech.edu/CaltechAUTHORS:BENpnas67

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Abstract

Complex as it is, much of the vast network of cellular functions has been successfully dissected, on a microscopic scale, by the use of mutants in which one element is altered at a time. A similar approach may be fruitful in tackling the complex structures and events underlying behavior, using behavioral mutations to indicate modifications of the nervous system. Drosophila offers the same advantages to such a study as it did to classical genetics, namely, large numbers and short generation time, to which may now be added an enormous store of accumulated knowledge concerning the organism. Containing about 105 neurons, the fly's nervous system is roughly halfway, on a logarithmic scale, between a single neuron and the human brain, and the fly is possessed of a rich repertoire of behavior. The considerable literature on Drosophila behavior since Carpenter's 1905 paper [1] has recently been reviewed by Manning.[2]


Item Type:Article
Related URLs:
URLURL TypeDescription
https://doi.org/10.1073/pnas.58.3.1112DOIArticle
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC335755/PubMed CentralArticle
Additional Information:© 1967 by the National Academy of Sciences Communicated June 28, 1967 The author is grateful to Dr. Roger Sperry for extending the hospitality of his laboratory and providing an introduction to the field of behavior, to Dr. E. B. Lewis for invaluable advice and a generous supply of Drosophila, and to Eveline Eichenberger for excellent technical assistance. This work was supported by a grant from the National Science Foundation (G-22122).
Funders:
Funding AgencyGrant Number
NSFG-22122
PubMed Central ID:PMC335755
Record Number:CaltechAUTHORS:BENpnas67
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:BENpnas67
Alternative URL:http://www.pnas.org/content/vol58/issue3/
Official Citation:BEHAVIORAL MUTANTS OF Drosophila ISOLATED BY COUNTERCURRENT DISTRIBUTION Seymour Benzer Proceedings of the National Academy of Sciences Sep 1967, 58 (3) 1112-1119; DOI: 10.1073/pnas.58.3.1112
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:5225
Collection:CaltechAUTHORS
Deposited By: Archive Administrator
Deposited On:05 Oct 2006
Last Modified:01 Mar 2019 16:41

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