Dyllick-Brenzinger, Christina and Sullivan, Glenn R. and Pang, Patty P. and Roberts, John D. (1980) Self-Association and Base Pairing of Guanosine, Cytidine, Adenosine, and Uridine in Dimethyl Sulfoxide Solution Measured by 15N Nuclear Magnetic Resonance Spectroscopy. Proceedings of the National Academy of Sciences of the United States of America, 77 (8). pp. 5580-5582. ISSN 0027-8424. https://resolver.caltech.edu/CaltechAUTHORS:DYLpnas80
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Abstract
The self-association of guanosine, cytidine, and adenosine and base pairing between guanosine, cytidine, adenosine, and uridine in dimethyl sulfoxide have been investigated by the variation of their 15N NMR chemical shifts with concentration and temperature. Guanosine, cytidine, and adenosine all showed evidence of self-association by hydrogen bonding. In guanosine/cytidine mixtures, a hydrogen-bonded dimer is formed; however, no base pairing could be detected with adenosine/cytidine or adenosine/uridine mixtures.
Item Type: | Article | ||||||
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Additional Information: | Copyright © 1980 by the National Academy of Sciences Contributed by John D. Roberts, May 22, 1980 This is contribution no. 6283 from the Gates and Crellin Laboratories of Chemistry. These studies were supported by the National Science Foundation and by the U.S. Public Health Service, Grant GM-11072 from the Division of General Medical Sciences. The National Science Foundation also provided a Summer Undergraduate Research Fellowship (Grant EPP 75-04744) for P.P.P. | ||||||
Subject Keywords: | nucleosides | ||||||
Issue or Number: | 8 | ||||||
Record Number: | CaltechAUTHORS:DYLpnas80 | ||||||
Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:DYLpnas80 | ||||||
Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | ||||||
ID Code: | 5236 | ||||||
Collection: | CaltechAUTHORS | ||||||
Deposited By: | Archive Administrator | ||||||
Deposited On: | 05 Oct 2006 | ||||||
Last Modified: | 02 Oct 2019 23:20 |
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