Landegren, Ulf and Kaiser, Robert and Caskey, C. Thomas and Hood, Leroy (1988) DNA diagnostics--molecular techniques and automation. Science, 242 (4876). pp. 229-237. ISSN 0036-8075. doi:10.1126/science.3051381. https://resolver.caltech.edu/CaltechAUTHORS:20141223-081324341
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Abstract
Molecular biology has revolutionized the understanding of many aspects of human disease. Ongoing developments in DNA diagnostics--the analysis of disease at the nucleic acid level--will soon provide automated, rapid, and inexpensive analyses for DNA or RNA sequences associated with genetic, malignant, and infectious diseases. DNA diagnostics will also facilitate the identification of disease-associated genes at birth, thus creating new opportunities for preventive medicine.
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Additional Information: | © 1988 American Association for the Advancement of Science. The authors gratefully acknowledge support from NSF to U.L., R.K., and L.H. and from NIH, the Muscular Dystrophy Foundation, and Howard Hughes Medical Institute to C.T.C. We thank N. Arnheim, W. Grody, C. Epstein, J. Korenberg, and M. Muldoon for useful advice. C. Hoog, T. Hunkapiller, W. Laug, D. Nickerson, and B. Popko offered helpful criticism on the manuscript. | ||||||||||||
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Issue or Number: | 4876 | ||||||||||||
DOI: | 10.1126/science.3051381 | ||||||||||||
Record Number: | CaltechAUTHORS:20141223-081324341 | ||||||||||||
Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20141223-081324341 | ||||||||||||
Official Citation: | DNA diagnostics--molecular techniques and automation U Landegren, R Kaiser, CT Caskey, and L Hood Science 14 October 1988: 242 (4876), 229-237. [DOI:10.1126/science.3051381] | ||||||||||||
Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | ||||||||||||
ID Code: | 53129 | ||||||||||||
Collection: | CaltechAUTHORS | ||||||||||||
Deposited By: | Tony Diaz | ||||||||||||
Deposited On: | 23 Dec 2014 16:34 | ||||||||||||
Last Modified: | 10 Nov 2021 19:48 |
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