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DNA diagnostics--molecular techniques and automation

Landegren, Ulf and Kaiser, Robert and Caskey, C. Thomas and Hood, Leroy (1988) DNA diagnostics--molecular techniques and automation. Science, 242 (4876). pp. 229-237. ISSN 0036-8075. http://resolver.caltech.edu/CaltechAUTHORS:20141223-081324341

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Abstract

Molecular biology has revolutionized the understanding of many aspects of human disease. Ongoing developments in DNA diagnostics--the analysis of disease at the nucleic acid level--will soon provide automated, rapid, and inexpensive analyses for DNA or RNA sequences associated with genetic, malignant, and infectious diseases. DNA diagnostics will also facilitate the identification of disease-associated genes at birth, thus creating new opportunities for preventive medicine.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1126/science.3051381DOIArticle
http://www.sciencemag.org/content/242/4876/229PublisherArticle
http://www.jstor.org/stable/1702185JSTORArticle
Additional Information:© 1988 American Association for the Advancement of Science. The authors gratefully acknowledge support from NSF to U.L., R.K., and L.H. and from NIH, the Muscular Dystrophy Foundation, and Howard Hughes Medical Institute to C.T.C. We thank N. Arnheim, W. Grody, C. Epstein, J. Korenberg, and M. Muldoon for useful advice. C. Hoog, T. Hunkapiller, W. Laug, D. Nickerson, and B. Popko offered helpful criticism on the manuscript.
Funders:
Funding AgencyGrant Number
NSFUNSPECIFIED
NIHUNSPECIFIED
Muscular Dystrophy FoundationUNSPECIFIED
Howard Hughes Medical Institute (HHMI)UNSPECIFIED
Record Number:CaltechAUTHORS:20141223-081324341
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:20141223-081324341
Official Citation:DNA diagnostics--molecular techniques and automation U Landegren, R Kaiser, CT Caskey, and L Hood Science 14 October 1988: 242 (4876), 229-237. [DOI:10.1126/science.3051381]
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:53129
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:23 Dec 2014 16:34
Last Modified:23 Dec 2014 16:34

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