Johann, Timothy W. and Barton, Jacqueline K. (1996) Recognition of DNA by Octahedral Coordination Complexes. Philosophical Transactions A: Mathematical, Physical and Engineering Sciences, 354 (1706). pp. 299-324. ISSN 1364-503X. https://resolver.caltech.edu/CaltechAUTHORS:20150107-105109518
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Abstract
Strategies for the site-specific recognition of DNA are described through the design of a family of octahedral metallointercalating complexes. Coordination complexes, which mimic DNA-binding proteins with regard to their affinity and specificity for DNA sites, may be prepared by the specific functionalization of chiral metal complexes so as to achieve the ensemble of non-covalent contacts in the DNA major groove anchored through intercalation.
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Additional Information: | © 1996 The Royal Society. We thank the National Institutes of Health for their financial support of this work. In addition, we are grateful to our co-workers and collaborators as denoted in the accompanying references. | ||||||
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Issue or Number: | 1706 | ||||||
Record Number: | CaltechAUTHORS:20150107-105109518 | ||||||
Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20150107-105109518 | ||||||
Official Citation: | Recognition of DNA by Octahedral Coordination Complexes Timothy W. Johann and Jacqueline K. Barton Philosophical Transactions: Mathematical, Physical and Engineering Sciences Vol. 354, No. 1706, Advances in Coordination Chemistry (Feb. 15, 1996) , pp. 299-324 Published by: The Royal Society Stable URL: http://www.jstor.org/stable/54648 | ||||||
Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | ||||||
ID Code: | 53269 | ||||||
Collection: | CaltechAUTHORS | ||||||
Deposited By: | Tony Diaz | ||||||
Deposited On: | 07 Jan 2015 20:20 | ||||||
Last Modified: | 03 Oct 2019 07:48 |
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