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Recognition of DNA by Octahedral Coordination Complexes

Johann, Timothy W. and Barton, Jacqueline K. (1996) Recognition of DNA by Octahedral Coordination Complexes. Philosophical Transactions A: Mathematical, Physical and Engineering Sciences, 354 (1706). pp. 299-324. ISSN 1364-503X . http://resolver.caltech.edu/CaltechAUTHORS:20150107-105109518

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Abstract

Strategies for the site-specific recognition of DNA are described through the design of a family of octahedral metallointercalating complexes. Coordination complexes, which mimic DNA-binding proteins with regard to their affinity and specificity for DNA sites, may be prepared by the specific functionalization of chiral metal complexes so as to achieve the ensemble of non-covalent contacts in the DNA major groove anchored through intercalation.


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http://www.jstor.org/stable/54648JSTORArticle
ORCID:
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Barton, Jacqueline K.0000-0001-9883-1600
Additional Information:© 1996 The Royal Society. We thank the National Institutes of Health for their financial support of this work. In addition, we are grateful to our co-workers and collaborators as denoted in the accompanying references.
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Record Number:CaltechAUTHORS:20150107-105109518
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:20150107-105109518
Official Citation:Recognition of DNA by Octahedral Coordination Complexes Timothy W. Johann and Jacqueline K. Barton Philosophical Transactions: Mathematical, Physical and Engineering Sciences Vol. 354, No. 1706, Advances in Coordination Chemistry (Feb. 15, 1996) , pp. 299-324 Published by: The Royal Society Stable URL: http://www.jstor.org/stable/54648
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:53269
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:07 Jan 2015 20:20
Last Modified:26 Jan 2016 19:47

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