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Chemical biology: Hitting the sweet spot

Tirrell, David A. (2004) Chemical biology: Hitting the sweet spot. Nature, 430 (7002). p. 837. ISSN 0028-0836. doi:10.1038/430837a.

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Delivering chemical agents to specific locations in the body has been an elusive goal ever since Paul Erhlich described his concept of the ‘magic bullet’ nearly a century ago.Whether the objective is delivering drugs to sites of injury and disease, or the infusion of imaging agents that allow physicians to see what is going on, one would like to be able to target molecules to the places where they are needed most. Ideally, one would be able to pick out a single cell (such as a cancer cell) in the midst of many others, and deliver a molecular payload to that cell alone.

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Tirrell, David A.0000-0003-3175-4596
Additional Information:© 2004 Nature Publishing Group.
Issue or Number:7002
Record Number:CaltechAUTHORS:20150121-093748562
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Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:53288
Deposited By: Anne Hormann
Deposited On:22 Jan 2015 22:22
Last Modified:10 Nov 2021 20:00

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