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Feeling the Pressure: Structural Insights into a Gated Mechanosensitive Channel

Spencer, Robert H. and Chang, Geoffrey and Rees, Douglas C. (1999) Feeling the Pressure: Structural Insights into a Gated Mechanosensitive Channel. Current Opinion in Structural Biology, 9 (4). pp. 448-454. ISSN 0959-440X. doi:10.1016/S0959-440X(99)80063-3.

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The structure determination of the large-conductance mechanosensitive channel (MscL) from Mycobacterium tuberculosis has revealed the architecture of the first full-length, gated pentameric ion channel. This structure provides insights into the elements participating in the conductance and gating mechanisms of these channels.

Item Type:Article
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URLURL TypeDescription ErrataErratum
Rees, Douglas C.0000-0003-4073-1185
Additional Information:© 1999 Published by Elsevier Ltd. The contributions of AT Lee and MT Barclay to the Tb-MscL structural studies arc greatly appreciated. RHS and GC contributed equally to this work.
Issue or Number:4
Record Number:CaltechAUTHORS:20150108-155745445
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Official Citation:Robert H Spencer, Geoffrey Chang, Douglas C Rees, ‘Feeling the pressure’: structural insights into a gated mechanosensitive channel, Current Opinion in Structural Biology, Volume 9, Issue 4, August 1999, Pages 448-454, ISSN 0959-440X, (
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:53422
Deposited By: SWORD User
Deposited On:13 Jan 2015 16:39
Last Modified:10 Nov 2021 20:01

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