CaltechAUTHORS
  A Caltech Library Service

Controlling absorbency in gelatin networks: Preparation and characterization of alkylated, crosslinked gelatin

Kiick-Fischer, Kristi L. and Tirrell, David A. (1998) Controlling absorbency in gelatin networks: Preparation and characterization of alkylated, crosslinked gelatin. Journal of Applied Polymer Science, 68 (2). pp. 281-292. ISSN 0021-8995. https://resolver.caltech.edu/CaltechAUTHORS:KIIjaps1998

Full text is not posted in this repository. Consult Related URLs below.

Use this Persistent URL to link to this item: https://resolver.caltech.edu/CaltechAUTHORS:KIIjaps1998

Abstract

Gelatin is a highly abundant and relatively inexpensive protein which is used in a variety of gel applications including photography, drug delivery, microencapsulation, and food preparation. Control of network formation in gelatin may therefore provide methods of preparing protein gels tailored for specific applications. In this study, circular dichroism (CD), Raman, and nuclear magnetic resonance (NMR) spectroscopies were used to characterize ordering processes which occur in gelatin and their relationship to absorbency. Ordering of the unmodified protein, studied as a function of concentration, temperature, and time after initial preparation, correlates inversely with absorbency. Chemical modification was used to control the absorbency and solubility of the protein gels. Alkylation of gelatin using glycidyltrimethylammonium chloride causes substantial increases in water absorbency with degrees of substitution as low as 0.5%. Increases in saline swelling were observed only after additional modification of the alkylated gelatin with a nonionic polyoxyalkyleneamine crosslinking agent (Jeffamine®). Limiting the initial degree of substitution prior to crosslinking (to just below 1%) plays a key role in optimizing the absorbency and minimizing the dissolution of the gel in saline. The methods and principles used to manipulate the absorbency of gelatin may also find use for other natural protein systems.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1002/(SICI)1097-4628(19980411)68:2<281::AID-APP10>3.0.CO;2-0DOIArticle
ORCID:
AuthorORCID
Kiick-Fischer, Kristi L.0000-0001-8587-0301
Tirrell, David A.0000-0003-3175-4596
Additional Information:© 1998 John Wiley & Sons. This work was supported under a collaborative agreement between Kimberly-Clark Corp. and the Center for University of Massachusetts-Industry Research on Polymers at the University of Massachusetts Amherst. NMR spectra were recorded in the University of Massachusetts NMR Facility, which is supported in part by the NSF Materials Science and Engineering Research Center at the University.
Funders:
Funding AgencyGrant Number
Kimberly-Clark Corp.UNSPECIFIED
University of MassachusettsUNSPECIFIED
NSFUNSPECIFIED
Subject Keywords:absorbents;proteins;gelatin;protein modification
Issue or Number:2
Record Number:CaltechAUTHORS:KIIjaps1998
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:KIIjaps1998
Official Citation:Kiick-fischer, K. L. and Tirrell, D. A. (1998), Controlling absorbency in gelatin networks: Preparation and characterization of alkylated, crosslinked gelatin. J. Appl. Polym. Sci., 68: 281–292. doi: 10.1002/(SICI)1097-4628(19980411)68:2<281::AID-APP10>3.0.CO;2-0
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:53438
Collection:CaltechAUTHORS
Deposited By: Anne Hormann
Deposited On:31 Jan 2015 23:50
Last Modified:28 Feb 2020 00:20

Repository Staff Only: item control page