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Biomembrane Templates for Nanoscale Conduits and Networks

Evans, Evan and Bowman, Howard and Leung, Andrew and Needham, David and Tirrell, David (1996) Biomembrane Templates for Nanoscale Conduits and Networks. Science, 273 (5277). pp. 933-935. ISSN 0036-8075. doi:10.1126/science.273.5277.933.

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Long nanotubes of fluid-lipid bilayers can be used to create templates for photochemical polymerization into solid-phase conduits and networks. Each nanotube is pulled from a micropipette-held feeder vesicle by mechanical retraction of the vesicle after molecular bonding to a rigid substrate. The caliber of the tube is controlled precisely in a range from 20 to 200 nanometers merely by setting the suction pressure in the micropipette. Branched conduits can be formed by coalescing separate nanotubes drawn serially from the feeder vesicle surface. Single nanotubes and nanotube junctions can be linked together between bonding sites on a surface to create a functionalized network. After assembly, the templates can be stabilized by photoinitiated radical cross-linking of macromonomers contained in the aqueous solution confined by the lipid bilayer boundary.

Item Type:Article
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Tirrell, David0000-0003-3175-4596
Additional Information:© 1996 American Association for the Advancement of Science. 4 March 1996; accepted 29 May 1996. This development was motivated by the Canadian Institute for Advanced Research Program in Science of Soft Surfaces and Interfaces. Additional support came from Canadian Medical Research Council grant MT 7477 (E.E.), the University of Massachusetts Materials Science and Engineering Center (D.T.), and North Carolina Biotechnology Center grant 9413 ARG-0018 (D.N. and E.E.).
Funding AgencyGrant Number
Canadian Institute for Advanced Research (CIfAR)UNSPECIFIED
Canadian Medical Research CouncilMT 7477
University of Massachusetts, Materials Science and Engineering CenterUNSPECIFIED
North Carolina Biotechnology Center9413 ARG-0018
Issue or Number:5277
Record Number:CaltechAUTHORS:EVAs1996
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Official Citation:Biomembrane Templates for Nanoscale Conduits and Networks Evan Evans, Howard Bowman, Andrew Leung, David Needham, and David Tirrell Science 16 August 1996: 273 (5277), 933-935. [DOI:10.1126/science.273.5277.933]
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:53446
Deposited By: Anne Hormann
Deposited On:29 Jan 2015 23:11
Last Modified:10 Nov 2021 20:02

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