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Application of scanning electrochemical microscopy to biological samples

Lee, Chongmok and Kwak, Juhyoun and Bard, Allen J. (1990) Application of scanning electrochemical microscopy to biological samples. Proceedings of the National Academy of Sciences of the United States of America, 87 (5). pp. 1740-1743. ISSN 0027-8424. https://resolver.caltech.edu/CaltechAUTHORS:20150113-115051446

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Abstract

The scanning electrochemical microscope can be used in the feedback mode in two-dimensional scans over biological substrates to obtain topographic information at the micrometer level. In this mode, the effect of distance between a substrate (either conductive or insulating) and a scanning ultramicroelectrode tip on the electrolytic current flowing at the tip is recorded as a function of the tip x-y position. Scans of the upper surface of a grass leaf and the lower surface of a Ligustrum sinensis leaf (which show open stomata structures) immersed in aqueous solution are shown. Scans of the upper surface of an elodea leaf in the dark and under irradiation, where the tip reaction is the reduction of oxygen produced by photosynthesis, demonstrate the possibility of obtaining information about the distribution of reaction sites on the substrate surface.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1073/pnas.87.5.1740DOIArticle
http://www.pnas.org/content/87/5/1740PublisherArticle
Additional Information:© 1990 National Academy of Sciences. Contributed by Allen J. Bard, December 18, 1989. The authors appreciate helpful discussions and advice by Dr. Ki Joong Kim. The support of this research by the Robert A. Welch Foundation and the National Science Foundation (CHE8901450) is gratefully acknowledged.
Funders:
Funding AgencyGrant Number
Robert A. Welch FoundationUNSPECIFIED
NSFCHE8901450
Issue or Number:5
Record Number:CaltechAUTHORS:20150113-115051446
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20150113-115051446
Official Citation:Lee, C., Kwak, J., & Bard, A. J. (1990). Application of scanning electrochemical microscopy to biological samples. Proceedings of the National Academy of Sciences, 87(5), 1740-1743.
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:53629
Collection:CaltechAUTHORS
Deposited By: Jason Perez
Deposited On:13 Jan 2015 22:53
Last Modified:03 Oct 2019 07:51

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