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How T Cells Count

Rothenberg, Ellen V. (1996) How T Cells Count. Science, 273 (5271). pp. 78-79. ISSN 0036-8075. doi:10.1126/science.273.5271.78. https://resolver.caltech.edu/CaltechAUTHORS:20150114-094250570

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Abstract

The rules by which the T cells of the immune system are activated by foreign peptides have seemed inconsistent and counterintuitive. In this week's issue, Viola et al. (p. 104) report that the T cells actually count how many T cell receptors are engaged. When the number 8000 is reached, the T cell becomes activated. In her Perspective, Rothenberg describes the many questions this discovery resolves.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/ 10.1126/science.273.5271.78DOIArticle
http://www.sciencemag.org/content/273/5271/78PublisherArticle
http://www.jstor.org/stable/2890046JSTORArticle
ORCID:
AuthorORCID
Rothenberg, Ellen V.0000-0002-3901-347X
Additional Information:© 1996 American Association for the Advancement of Science.
Issue or Number:5271
DOI:10.1126/science.273.5271.78
Record Number:CaltechAUTHORS:20150114-094250570
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20150114-094250570
Official Citation:How T Cells Count Ellen V. Rothenberg Science 5 July 1996: 273 (5271), 78. [DOI:10.1126/science.273.5271.78]
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:53679
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:14 Jan 2015 17:47
Last Modified:10 Nov 2021 20:05

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