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Mammalian Muscle Acetylcholine Receptor: A Supramolecular Structure Formed by Four Related Proteins

Conti-Tronconi, Bianca M. and Gotti, Cecilia M. and Hunkapiller, Michael W. and Raftery, Michael A. (1982) Mammalian Muscle Acetylcholine Receptor: A Supramolecular Structure Formed by Four Related Proteins. Science, 218 (4578). pp. 1227-1229. ISSN 0036-8075. doi:10.1126/science.7146904. https://resolver.caltech.edu/CaltechAUTHORS:20150121-084336620

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Abstract

The nicotinic acetylcholine receptor has been purified from fetal calf muscle. Amino terminal amino acid sequence data indicate that the mammalian receptor is formed from closely related but distinct subunits. A cytoskeletal component, actin, may be associated with the receptor.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1126/science.7146904DOIArticle
http://www.sciencemag.org/content/218/4578/1227PublisherArticle
http://www.jstor.org/stable/1688999JSTORArticle
Additional Information:© 1982 American Association for the Advancement of Science. Received 24 May 1982; revised 24 September 1982. This research was supported by USPHS NS-10294 and GM-06965 and by grants from the Muscular Dystrophy Association of America, the Myasthenia Gravis Foundation (Los Angeles Chapter), the Pew Charitable Trust, and the Weingart Foundation. We thank John Racs and Laurie Jutzi for technical assistance.
Funders:
Funding AgencyGrant Number
U. S. Public Health Service (USPHS)NS-10294
U. S. Public Health Service (USPHS)GM-06965
Muscular Dystrophy Association of AmericaUNSPECIFIED
Myasthenia Gravis FoundationUNSPECIFIED
Pew Charitable TrustUNSPECIFIED
Weingart FoundationUNSPECIFIED
Issue or Number:4578
DOI:10.1126/science.7146904
Record Number:CaltechAUTHORS:20150121-084336620
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20150121-084336620
Official Citation:Mammalian muscle acetylcholine receptor: a supramolecular structure formed by four related proteins BM Conti-Tronconi, CM Gotti, MW Hunkapiller, and MA Raftery Science 17 December 1982: 218 (4578), 1227-1229. [DOI:10.1126/science.7146904]
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:53922
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:21 Jan 2015 23:27
Last Modified:10 Nov 2021 20:24

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