Maeda, Mizuo and Kumano, Atsushi and Tirrell, David A. (1991) Signal-Sensitive Release of Contents from Liposomes Bearing Surface-Grafted Polyelectrolyte Chains. Annals of the New York Academy of Sciences, 618 (Temporal). pp. 362-366. ISSN 0077-8923. doi:10.1111/j.1749-6632.1991.tb27256.x. https://resolver.caltech.edu/CaltechAUTHORS:20150121-145328933
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Abstract
Therapeutic advantages of signal-sensitive drug delivery are easily imagined. Current dosage methods are most often empirically based, and only rarely reflect the actual time dependence of the patient's therapeutic need. In principle, self-regulated delivery systems would reduce the administered dose to a minimum while maintaining a therapeutically effective concentration of the agent at the target site. In practice, the routine application of self-regulated delivery systems remains relatively remote.
| Item Type: | Article | |||||||||
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| Additional Information: | © 1991 New York Academy of Sciences. Special Issue: Temporal Control of Drug Delivery. This work was supported in part by a grant from the U.S. Army Research Office (DAAL03–88-K-0038) and in part by a Presidential Young Investigator Award of the National Science Foundation (to D.A.T.). | |||||||||
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| Issue or Number: | Temporal | |||||||||
| DOI: | 10.1111/j.1749-6632.1991.tb27256.x | |||||||||
| Record Number: | CaltechAUTHORS:20150121-145328933 | |||||||||
| Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20150121-145328933 | |||||||||
| Official Citation: | MAEDA, M., KUMANO, A. and TIRRELL, D. A. (1991), Signal-Sensitive Release of Contents from Liposomes Bearing Surface-Grafted Polyelectrolyte Chains. Annals of the New York Academy of Sciences, 618: 362–366. doi: 10.1111/j.1749-6632.1991.tb27256.x | |||||||||
| Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | |||||||||
| ID Code: | 53961 | |||||||||
| Collection: | CaltechAUTHORS | |||||||||
| Deposited By: | Katherine Johnson | |||||||||
| Deposited On: | 21 Jan 2015 23:00 | |||||||||
| Last Modified: | 10 Nov 2021 20:25 |
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