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Mouse Interferons: Amino Terminal Amino Acid Sequences of Various Species

Taira, Hideharu and Broeze, Robert J. and Jayaram, Bettadapura M. and Lengyel, Peter and Hunkapiller, Michael W. and Hood, Leroy E. (1980) Mouse Interferons: Amino Terminal Amino Acid Sequences of Various Species. Science, 207 (4430). pp. 528-530. ISSN 0036-8075. doi:10.1126/science.7352261.

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Mouse interferons of three size classes (A, 35,000 to 40,000 daltons; B, 26,000 to 33,000 daltons; and C, 20,000 daltons) were purified from Ehrlich ascites tumor cells infected with Newcastle disease virus. The sequences of the first 24 amino acids (No.17 has not been identified) of interferons A and B are identical. The sequence of the first 20 amino acids of interferon C differs from that of A and B in 18 positions. There is partial homology in amino terminal sequence between mouse interferons A (or B) and a human fibroblast interferon and between mouse interferon C and a human lymphoblastoid interferon.

Item Type:Article
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Hood, Leroy E.0000-0001-7158-3678
Additional Information:© 1980 American Association for the Advancement of Science. 30 November 1979. Supportedb y NIH grants CA16038 and AI12320 and by a grant from the Weingart Foundation Los Angeles, Calif. We thank E. Slattery for advice in producing in terferons and T. Novicki and M. Gomez for technical assistance.
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Weingart FoundationUNSPECIFIED
Issue or Number:4430
Record Number:CaltechAUTHORS:20150202-074659790
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Official Citation:Mouse Interferons: Amino Terminal Amino Acid Sequences of Various Species Hideharu Taira, Robert J. Broeze, Bettadapura M. Jayaram, Peter Lengyel, Michael W. Hunkapiller and Leroy E. Hood Science New Series, Vol. 207, No. 4430 (Feb. 1, 1980) , pp. 528-530 Published by: American Association for the Advancement of Science Stable URL:
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:54272
Deposited By: Ruth Sustaita
Deposited On:02 Feb 2015 17:44
Last Modified:10 Nov 2021 20:31

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