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Molecular Biology of the Sea Urchin Embryo

Davidson, Eric H. and Hough-Evans, Barbara R. and Britten, Roy J. (1982) Molecular Biology of the Sea Urchin Embryo. Science, 217 (4554). pp. 17-26. ISSN 0036-8075. doi:10.1126/science.6178156.

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Research on the early development of the sea urchin offers new insights into the process of embryogenesis. Maternal messenger RNA stored in the unfertilized egg supports most of the protein synthesis in the early embryo, but the structure of maternal transcripts suggests that additional functions are also possible. The overall developmental patterns of transcription and protein synthesis are known, and current measurements describe the expression of specific genes, including the histone genes, the ribosomal genes, and the actin genes. Possible mechanisms of developmental commitment are explored for regions of the early embryo that give rise to specified cell lineages, such as the micromere-mesenchyme cell lineage.

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Additional Information:© 1982 American Association for the Advancement of Science. We are most grateful to colleagues who have given us the benefit of their various perspectives in critically reviewing this manuscript, in particular Fred Wilt of the University of California, Berkeley, Thorn Pederson of the Worcester Foundation, and Lee Hood, James Strauss, Herschel Mitchell, and Barbara Wold of the Division of Biology. Research from this laboratory was supported by NICHD grants HD05753, GM20927, and RR00986 and by NSF grant PCM-8004072.
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Issue or Number:4554
Record Number:CaltechAUTHORS:20150204-145027606
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Official Citation:Molecular biology of the sea urchin embryo EH Davidson, BR Hough-Evans, and RJ Britten Science 2 July 1982: 217 (4554), 17-26. [DOI:10.1126/science.6178156]
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:54383
Deposited By: Ruth Sustaita
Deposited On:05 Feb 2015 04:58
Last Modified:10 Nov 2021 20:32

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