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DNA Sequence of a Gene Encoding a BALB/c Mouse L^d Transplantation Antigen

Moore, Kevin W. and Sher, Beverly Taylor and Sun, Y. Henry and Eakle, Kurt Andrew and Hood, Leroy (1982) DNA Sequence of a Gene Encoding a BALB/c Mouse L^d Transplantation Antigen. Science, 215 (4533). pp. 679-682. ISSN 0036-8075. http://resolver.caltech.edu/CaltechAUTHORS:20150204-153430736

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Abstract

The sequence of a gene, denoted 27.5, encoding a transplantation antigen for the BALB/c mouse has been determined. Gene transfer studies and comparison of the translated sequence with the partial amino acid sequence of the L^d transplantation antigen establish that gene 27.5 encodes an L^d polypeptide. A comparison of the gene 27.5 sequence with several complementary DNA sequences suggests that the BALB/c mouse may contain a number of closely related L-like genes. Gene 27.5 has eight exons that correlate with the structural domains of the transplantation antigen.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1126/science.7058332DOIArticle
http://www.sciencemag.org/content/215/4533/679.abstractPublisherArticle
http://www.jstor.org/stable/1688212JSTORArticle
Additional Information:© 1982 American Association for the Advancement of Science. 5 November 1981 ; revised 16 December 1981. Supported by NIH grant GM 06965. K.W.M. was initially supported by a postdoctoral fellowship from the National Institutes of Health. B.T.S. was supported by a predoctoral fellowship from the National Science Foundation. Y.H.S. and K.A.E.were supported by a national research service award (I T32 GM07616) from the National Institute of General Medical Sciences. We thank M. Douglas for computer graphics, T. Hunkapiller for computer programs, and B. Larsh for manuscript preparation. We thank W. R. Jelinek for pointing out the presence of several Alu-like sequences in gene 27.1.
Funders:
Funding AgencyGrant Number
NIHGM 06965
NIH FellowshipUNSPECIFIED
NSF Predoctoral FellowshipUNSPECIFIED
National Institute of General Medical SciencesI T32 GM07616
Record Number:CaltechAUTHORS:20150204-153430736
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:20150204-153430736
Official Citation:DNA sequence of a gene encoding a BALB/c mouse Ld transplantation antigen KW Moore, BT Sher, YH Sun, KA Eakle, and L Hood Science 5 February 1982: 215 (4533), 679-682. [DOI:10.1126/science.7058332]
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:54391
Collection:CaltechAUTHORS
Deposited By: Ruth Sustaita
Deposited On:05 Feb 2015 04:54
Last Modified:05 Feb 2015 04:54

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