Kim, Jongsun and Rees, Douglas C. (1994) Nitrogenase and Biological Nitrogen Fixation. Biochemistry, 33 (2). pp. 389-397. ISSN 0006-2960. https://resolver.caltech.edu/CaltechAUTHORS:20150205-141446723
Full text is not posted in this repository. Consult Related URLs below.
Use this Persistent URL to link to this item: https://resolver.caltech.edu/CaltechAUTHORS:20150205-141446723
Abstract
Biological nitrogen fixation is catalyzed by the nitrogenase enzyme system which consists of two metalloproteins, the iron (Fe-) protein and the molybdenum-iron (MoFe-) protein. Together, these proteins mediate the ATP-dependent reduction of dinitrogen to ammonia. Recent crystallographic analyses of Fe-protein and MoFe-protein have revealed the polypeptide fold and the structure and organization of the unusual metal centers in nitrogenase. These structure provide a molecular framework for addressing the mechanism of the nitrogenase-catalyzed reaction. General features of the nitrogenase system, including conformational coupling of nucleotide hydrolysis, aspects of the cluster structures, and the general spatial organization of redox centers within the protein subunits, are relevant to a wide range of biochemical systems.
| Item Type: | Article | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Related URLs: |
| |||||||||
| ORCID: |
| |||||||||
| Contact Email Address: | phoebe@caltech.edu | |||||||||
| Additional Information: | © 1994 American Chemical Society. Received September 28, 1993; Revised Manuscript Received November 12, 1993. Work in the authors' lab was supported by USPHS Grant GM45162 (Fe-protein) and NSF Grant DMB 91-18689 (MoFe-protein). The invaluable contributions of B. T. Hsu, M.M. Georgiadis, D. Woo, M.W. Day, M.K. Chan, H. Komiya, J.L. Schlessman, L. Joshua-Tor, A.J. Chirino, and M.H.B. Stowell to various phases of this project are deeply appreciated, as are numerous discussions with J.B. Howard. | |||||||||
| Funders: |
| |||||||||
| Issue or Number: | 2 | |||||||||
| Record Number: | CaltechAUTHORS:20150205-141446723 | |||||||||
| Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20150205-141446723 | |||||||||
| Official Citation: | Nitrogenase and biological nitrogen fixation Jongsun Kim and Douglas C. Rees Biochemistry 1994 33 (2), 389-397 | |||||||||
| Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | |||||||||
| ID Code: | 54448 | |||||||||
| Collection: | CaltechAUTHORS | |||||||||
| Deposited By: | SWORD User | |||||||||
| Deposited On: | 08 Feb 2015 02:47 | |||||||||
| Last Modified: | 03 Oct 2019 07:57 |
Repository Staff Only: item control page
