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| This is a comprehensive bibliography (under construction) of primary and secondary sources on the neutral theory of molecular evolution. It currently covers the period 1973-2001. |
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Author :
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Colgan, D. J.
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Year :
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1992
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Title :
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Interspecific Isozymic Substitution Is Not Random
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Journal :
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Heredity
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Volume :
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69
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Pages :
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150-159
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Date :
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Aug
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Short Title :
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Interspecific Isozymic Substitution Is Not Random
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Alternate Journal :
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Heredity
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Custom 2 :
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ISI:A1992JG28000008
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Abstract :
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The validity of the neutral theory of molecular evolution, which holds that almost all allelic substitution during evolution has been due to random genetic drift, is a pivotal question in evolutionary biology. Here it is shown that the theory predicts a 1:1 ratio among isozymes in a species between those which are faster (i.e. have greater anodal mobilities) and those which are slower (i.e. have lesser anodal mobilities) than their homologues in a related species. In fact, observed patterns of isozymic variation display deviations from such a ratio. Significant departures from expected values were found for reptiles, fish and insects. A near significant result was seen for amphibia. The overall deviations are highly significant. The results strongly suggest that a substantial fraction of allozymic substitution has been due to positive Darwinian selection.
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Notes :
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Times Cited: 2
2
JG280
HEREDITY
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| | -- contributed by John Beatty, March 29, 2002 |
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